Synonym(s)
HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Rare, diffuse, indurating panniculitis of immature newborns, usually occurring secondarily as a symptom of a life-threatening underlying disease.
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EtiopathogenesisThis section has been translated automatically.
Unsolved. Discussed are inadequate nutrition, infections, diarrhoea, cooling (observed after therapeutic hypothermia).
ManifestationThis section has been translated automatically.
Occurs from birth, especially between the 2nd and 10th day of life, in severe underlying diseases also in older children. There is a slight predominance of the male sex.
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Complication(s)This section has been translated automatically.
TherapyThis section has been translated automatically.
Symptomatic intensive medical care with circulation stabilisation, fluid and electrolyte stabilisation, regulation of body heat (incubator), tube feeding.
Progression/forecastThis section has been translated automatically.
Awkward. Rapid lethal outcome is possible. Mortality 50 to 85%. Death by sepsis.
LiteratureThis section has been translated automatically.
- Battin M et al (2002) Sclerema Neonatorum following hypothermia. J Paediatr Child Health 38: 533-534
- Darragh CT et al (2014) Sclerodermatous skin changes in an infant. Pediatric Dermatol 31:387-388
- de Silva U et al (1994) Historical approach to scleroderma. Clin Dermatol 12: 201-205
- Llamas-Velasco M et al (2015) Panniculitis with crystals induced by etanercept subcutaneous injection. J Cutan Pathol doi: 10.1111/cup.12478
- Navarini-Meury S et al (2007) Sclerema neonatorum after therapeutic whole-body hypothermia. Arch Dis Child Fetal Neonatal Ed 92: F307
- Requena L et al (2001) Panniculitis. Part II. Mostly lobular panniculitis. J Am Acad Dermatol 45: 325-361
Shrestha S et al (2017) Sclerema Neonatorum Treated Successfully with Parenteral Steroids: An Experience from a Resource Poor Country.Case Rep Pediatr 2017:4836142.
- Warwick W et al (1963) Sclerema neonatorum - a sign, not a disease. JAMA 184: 680-683
- Zeb A et al (2008) Sclerema neonatorum: a review of nomenclature, clinical presentation, histological features, differential diagnoses and management. J Perinatol 28:453-460
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Incoming links (5)
Adiposclerosis of the newborn; Sclerema; Sclerema neonatorum; Sclerema oedematosum neonatorum; Subcutaneous fat tissue necrosis of the newborn;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer