Synonym(s)
low-grade; myofibroblastic sarcoma
DefinitionThis section has been translated automatically.
Low malignant sarcoma of the deep connective tissue and the subcutis.
LocalizationThis section has been translated automatically.
Preferably located at the extremities.
You might also be interested in
Clinical featuresThis section has been translated automatically.
Differently sized subcutaneously localized painless tumor masses.
HistologyThis section has been translated automatically.
- Solid tumour whose spindly or star-shaped cells are arranged fascicularly or even storiformly. Pale eosinophilic cytoplasm. Oval nuclei with finely distributed chromatin. Multinucleated giant cells are often detectable, also focal mucinous degeneration.
- Immunohistology: HHF35 pos., alpha-SMA pos., desmin pos./neg., CD34 pos./neg., collagen type IV is focally detectable.
TherapyThis section has been translated automatically.
Excision with sufficient safety distance ( Mohs technique).
Note(s)This section has been translated automatically.
Some authors question the autonomy of the clinical picture. A fibroblastic/myofibroblastic differentiation can be found in various cutaneous sarcomas. A close histogenetic relationship between fibrosarcoma, malignant fibrous histiocytoma and myofibroblastic sarcoma is assumed.
LiteratureThis section has been translated automatically.
- Chang SE et al (2001) A case of cutaneous low-grade myofibroblastic sarcoma. J Dermatol 28: 383-387
- Diaz-Cascajo C et al (2003) Fibroblastic/myofibroblastic sarcoma of the skin: a report of five cases. J Cutan Pathol 30: 128-134
Recommended articles
Outgoing links (1)
Mohs technique;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer