Salvar sandstone dermatitis - Altmeyers Encyclopedia

Synonym(s)

arsenal eczema; Arsenic dermatitis

Definition
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Drug exanthema after Salvarsan therapy. Formerly frequent, today extremely rare.

Localization
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Spread according to the following order: forearms, neck, lower extremities, trunk.

Clinic
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Itching, regional erythema, extensive enlargement with formation of vesicles and pustules. Formation of a pronounced oedema of the eyelids and face, extensive oozing, crust formation, severe scaling. Tendency to rapid development of erythroderma. Transverse furrowing and loss of nails, alopecia. Additionally: toxic damage to internal organs. Duration of the disease: from a few months to two years.