Ranitidine
Definition
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H2 receptor blocker.
Indication
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Duodenal ulcers, benign stomach ulcers, reflux esophagitis, Zollinger-Ellison syndrome.
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Dosage and method of use
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Adults with normal kidney function: duodenal and benign gastric ulcers: 300 mg after dinner or before bed or 150 mg ranitidine twice a day (morning and evening).
Undesirable effects
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Hypersensitivity reactions, eosinophilia, urticaria, pruritus, fever, myalgias, pancreatitis; joint pain, headaches, fatigue, depression, confusion, hallucinations, transaminase and creatinine elevation, loss of libido, potency disorders, cardiac arrhythmia, drop in blood pressure, bronchospasm, pancytopenia, leukopenia and thrombopenia, agranulocytosis, acute tubulointerstitial nephritis.
Contraindication
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Children under 10 years; porphyria in the medical history.
Preparations
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Ranitidine-ratiopharm, Sostril, Zantic
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Prof. Dr. med. Peter Altmeyer