Powder

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Powder adspergendi; Zinc oxide-talcum powder 50% white or skin coloured (NRF 11.60.)

Definition
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Undivided powders intended for external use only (see table). Pure active ingredient powders or mixtures with two or more excipients (e.g. talcum, zinc oxide, titanium dioxide, white clay) and, if necessary, approved colouring agents (iron oxide, red clay) are produced. They should be as fine as possible, sterilizable (application on open wounds or irritated skin), completely non-irritating, chemically indifferent and indecomposable, have good adhesive and scattering properties as well as absorbency against liquids (water and oil).

Pharmacodynamics (Effect)
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Depending on composition cooling, drying, adsorbing, astringent:
  • Cooling effect: Starches, Zn or Al stearate.
  • Absorption: Aerosil, white clay, starches, microcrystalline cellulose.
  • Absorption without swelling: ANM, NAC and Nalcip.
  • Lubricity: Talc, Zn, Mg or Al stearate.
  • Adhesion: Talc, aerosil, starches, greases, Al hydroxide.
  • Spreadability: Aerosil and talc.
  • Hiding power: titanium dioxide, zinc oxide and Ca-carbonate.
  • Active substance absorption: lactose.

Indication
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Dermatoses in intertriginous areas as well as in epithelial losses.

Contraindication
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Weeping dermatoses (clumping and congestion of secretions and resulting secondary infections). Talcum powder on open wounds (silicate granulomas).

Recipe(s)
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Zinc oxide-talcum powder 50% white or skin-coloured NRF 11.60.(R294)

Tables
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Powder bases and their use in exteriors

Powder base

Use

Aluminium stearate

Adstringens

Iron oxides

Colour pigment for concealer powders, shaking mixtures and pastes

Lactose

Resorption improver

Magnesium carbonate

Absorption of secretions

Magnesium oxide

Absorption of secretions

Magnesium stearate

Adstringens

Maize starch

Improvement of adhesion and throwing power

Corn starch, phosphated

Improvement of adhesion and throwing power

Silicon dioxide, highly dispersed

Absorption of secretions, improvement of spreading ability

Talcum powder

Improvement of adhesion and throwing power

Titanium dioxide

Cover, light protection

clay, white

Absorption of secretions

Wheat starch

Adstringens

Zinc oxide

Coverage, improvement of throwing power

Zinc stearate

Adstringens

Authors

Last updated on: 29.10.2020