Pm-scl antibody

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Antibodies to a nucleolar antigen having molecular weights of 96, 80 and 75 kDa.

Occurrence
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Scleroderma, dermatomyositis, arthritis, arthralgias. Detection of PM-SCl antibodies is characteristic for an overlap syndrome with overlap of dermatomyositis and progressive systemic scleroderma, see below autoantibodies.

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Last updated on: 29.10.2020