Pasteurellose A28.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 04.04.2021

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History
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Lehmann and Neumann, 1899

Definition
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Bacterial infection that is mainly transmitted by animal bites and causes soft tissue infections in the wound area.

Pathogen
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Pasteurella multocida, more rarely P. dagmatis, P. canis, P. haemolyticus.

Pasteurella are Gram-negative, immotile, coccoid or ovoid rod-shaped bacteria found worldwide predominantly in the nasopharyngeal and gastrointestinal tracts of wild and domesticated mammals and birds.

Humans become infected from animals by bites and scratches, smear infection or aerogenic transmission.

Occurrence/Epidemiology
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Worldwide spread. Only in 5-15% of cases animal contact can be determined.

Manifestation
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Owners of pets or professionally exposed persons are particularly at risk.

Clinical features
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  • After an incubation period of 2-14 days (depending on the entry port of the pathogen), sometimes even after a few hours, erythema and pain in the wound area occur. Phlegmonous and abscessing inflammation may also occur as well as regional lymphadenitis. Progressive infection can also affect tendons, bones and joints. In addition, the sinuses and the entire respiratory tract (chronic bronchitis, pneumonia) can be affected.
  • Septic courses are possible with immunosuppression.
  • In individual cases conjunctivitis, stomatitis, enteritis, peritonitis, urinary tract infections and myositis.
  • Bacteremia and/or metastatic spread of lesions may occur.

Diagnosis
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Microscopy and culture of the biopsy or other samples.

Differential diagnosis
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Gas fire; staphylococcal, streptococcal, capnocytophaga infection; rat bite disease; cat scratch disease; tularaemia.

Therapy
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  • Penicillin V (e.g. Megacillin) 3 times/day 1.5 million IU p.o. or Doxycyclin 2 times/day 100 mg p.o. for 10-14 days.
  • Alternatively: Levofloxacin 2 times/day 500 mg p.o. for 7-14 days.
  • Surgical measures.

Note(s)
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Hygienic measures when handling animals.

Literature
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  1. Kristinsson G (2007) Pasteurella multocida infections. Pediatric Rev 28: 472-473
  2. Yokose N, Dan K (2007) Pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma. Int J Hematol 85: 146-148

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 04.04.2021