Panatrophia localisata L90.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Gowers disease; Gowers M.; Local panatrophy (Gowers); Panatrophia cutis localisata; Panatrophy of Gowers

History
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Gowers, 1886

Definition
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Rarely acquired, localized, partial or total loss of subcutaneous fatty tissue. Fatty tissue atrophy may be combined with atrophy of the underlying muscles and bones.

Etiopathogenesis
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Unsolved, in some cases corticoid crystal suspensions are accused. Connection with circumscribed scleroderma is discussed. A case of Panatrophia localisata in the area of a congenital melanocytic nevus (so-called bathing trunks nevus) has been described.

Manifestation
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Preferably affected are women between the 2nd and 4th decade of life.

Localization
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Mainly back, buttocks, extremities.

Clinical features
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Sharply defined, atrophic, hollowed, hyper- or depigmented skin area.

Histology
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Corium and epidermis thinned. Loss of subcutaneous fatty tissue.

Differential diagnosis
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Therapy
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  • No general causal therapy known. As far as possible, treatment of the cause.
  • As a consequence of circumscribed scleroderma: The therapy is based on the cosmetic need. Preferably plastic surgery corrections. Attempt at fat tissue augmentation.

Progression/forecast
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Suspension of the atrophic process within a few months.

Literature
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  1. Barnes S (1902) Report on Sir William Gowers' case of local panatrophy Transact Clin Soc London 36: 164-168
  2. Barnes S (1939) Gowers' case of local panatrophy. Br J Dermatol 51: 377-380
  3. Gowers W (1886) A Manual of Diseases of the Nervous system. Vol. 1, J. &. A. Churchill, London, p. 365
  4. Paliwal VK et al (2015) Panatrophy of Gowers is a rare disease: case reports and review of theliterature
    . Int J Dermatol 54:656-661.
  5. Sakamoto T et al (1998) Gowers' local panatrophy. Eur J Dermatol 8: 116-117

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Last updated on: 29.10.2020