Oxatomide
Definition
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Antiallergic.
Half-life
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18 h
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Indication
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Allergic rhinitis, urticaria, bronchial asthma.
Limited indication
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Pregnancy, lactation, glaucoma, urinary retention, liver dysfunction, Parkinson's syndrome, prostate hypertrophy.
Dosage and method of use
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- Adults: 2 times/day 30-60 mg p.o.
- Children 6-12 years: 2 times 0,5 mg/kg bw after meals.
Undesirable effects
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Allergic reactions, paragroup allergy (suspension), fatigue, influence on the ability to react, dyskinesia, extrapyramidal symptoms, opisthotonus, Parkinson's syndrome, weight gain, galactorrhea, gastrointestinal disorders, dry mouth, increase in transaminases, mamma hypertrophy.
Interactions
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Alcohol increases CNS attenuation, atropine sulphate and tricyclic antidepressants increase anticholinergic effects, aminoglycosides increase hearing damage.
Contraindication
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Paragroup allergy (suspension), children < 6 years.
Preparations
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Tinset