Nodules, rheumatic I00.0
Synonym(s)
Aschoff nodule; Aschoff's nodes; nodules rheumatici; Rheumatic granulomas; Rheumatic tendon nodules; tendon nodules rheumatic
History
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Hilliers, 1868
Definition
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Pea-sized nodules in rheumatic fever (30% of cases), located mainly above bony projections (fingers, elbows, back of the head). Heart involvement is frequent.
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Histology
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In the deep layers of the dermis, palisade granulomas of histiocytes, lymphocytes and various numbers of multinuclear giant cells are found. In the centre of the granuloma, eosinophilic, fibrinoid collagen necroses with nuclear residues as well as fibrin and mucin deposits can be seen.
Differential diagnosis
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Histological differential diagnoses:
- Rheumatic nodules (rheumatoid nodules)
- Lifting knots
- Gouty Tophi
- Granuloma anulare subcutaneum.
Therapy
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Treatment of the underlying disease. Otherwise no treatment is necessary. The nodules regress spontaneously.
Progression/forecast
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Reducible in a short time.
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Incoming links (11)
Aschoff nodule; Dermatofibroma; Gouty tophi; Granuloma; Lichen myxoedematosus discrete type ; Nodules rheumatici; Rheumatic fever; Rheumatic granulomas; Rheumatic nodules; Rheumatic tendon nodules; ... Show allOutgoing links (5)
Gouty tophi; Granuloma annulare subcutaneum; Heberden's knot; Rheumatic fever; Rheumatic nodules;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer
