Nimorazole
Definition
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Chemotherapeutic agent of the imidazole type.
Half-life
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3 h
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Indication
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Trichomoniasis, amoebiasis, lambliasis.
Limited indication
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Blood formation disorders, application > 10 days, active CNS diseases, severe liver and kidney diseases.
Dosage and method of use
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- Amoebiasis, Lambliasis: 2 times 1 g/day p.o. for 5-7 days; children 20-30 mg/kg bw/day.
- Trichomoniasis: 4 times 500 mg/day p.o. for 7 days (partner treatment!).
Undesirable effects
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Allergic reactions, potential carcinogenicity, headache, fatigue, agitation, dizziness, metallic taste, leukopenia, gastrointestinal disorders.
Interactions
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Reduced alcohol tolerance, increased bleeding tendency when taking coumarins.
Contraindication
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Pregnancy, lactation, imidazole hypersensitivity.
Preparations
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Esclama
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Prof. Dr. med. Peter Altmeyer