Niclosamide
Definition
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Pharmacodynamics (Effect)
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Vermicide by depletion of glucose and glycogen, inhibition of glycolysis.
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Spectrum of action
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Taenia saginata, taenia solium, Diphyllobothrium latum, Hymenolepsis nana.
Indication
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Taeniasis, infections with Diphyllobothria
Note! Niclosamide is not effective against larval stages ( cysticercosis
)!
Limited indication
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Pregnancy (strict indication in the 1st trimester).
Dosage and method of use
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- Adults and children > 6 years: 2 g as ED p.o.
- Children 2-6 years: 1 g.
- Children < 2 years: 500 mg.
Undesirable effects
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Headaches, gastrointestinal disorders, allergic reactions.
Interactions
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Reduced alcohol tolerance.
Preparations
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Yomesan
Patientinformation
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Remember! Take tablets at once unchewed or swallowed in water after breakfast. In case of constipation, ensure that the bowels are emptied before treatment!
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Prof. Dr. med. Peter Altmeyer