New recipe form

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

NRF

Definition
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Collection of German magistral formulae as part of the German Drug Codex (DAC). Prescriptions are still indispensable today, especially in niches of pharmacotherapy for which finished drugs are not available or not available in sufficient quantities. In general, formulations do not have a long shelf life in favour of good tolerability and are therefore produced without preservatives and stabilisers if required. This may be an essential advantage for the therapy of sensitive skin.

General information
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  • The establishment of the New Prescription Form (NRF) as an offshoot of the German Drug Codex ( DAC) was initiated around 1980. For dermatologists it stands for particularly safe pharmacy formulas. In the pharmacy the DAC/NRF service of the prescription information centre can be used for magistral prescriptions besides the manufacturing part.
  • The NRF has an important function in the pharmaceutical quality assurance of such drugs which are prescribed by prescription in the absence of suitable finished drugs within the scope of the medical freedom of therapy (see prescription below). This is also related to the "compassionate use" and the " orphan drug" problem. Corresponding niches of pharmacotherapy are mainly found in local application in dermatology, ear, nose and throat medicine, dentistry and special paediatric dosages.
  • Besides few preparations from the German Prescription Formulae (DRF; published 1950) which are obsolete in large parts, numerous regulations of the official collection of formulae in the GDR, the Standardrezepturen 1990 (SR), have been adapted for the "Neues Rezeptur Formularium".

Note(s)
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The standardised formulations described in the NRF can be produced perfectly in any pharmacy.

Literature
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  1. Reimann H (2011) The New Recipe Form (NRF) in the DAC. Abstract CD 46th DDG Conference K24/02 -

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Last updated on: 29.10.2020