Myointimom D18.01

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Myointimoma; Myointimom of the penis; Penile myointimoma; Peniles Myointimom

History
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Fetsch JF et al. 2000

Definition
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Penile myointimoma is a rare, benign, multinodular, myointimal, tumor formation that has been described so far exclusively in the corpus spongiosum of the glans penis and is most common in adult patients, less common in children. Since the first description in 2000 there are < 30 publications on this entity in the literature.

Manifestation
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The average age is 29 years (2- 61 years) (Fetsch JF et al. 2000)

Clinical features
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Painless, subcutaneous, firm, tumor, usually located in the glans penis, 0.4-1.8 cm in size (Turner BM et al. 2009).

Histology
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Multinodular, vascular, fragile and poorly delimitable, often occlusive, fibrointimal proliferation with plexiform architecture involving the vascular system of the Corpus spongiosum. Immunohistochemically there is a strong cytoplasmic immunoreactivity for actin and desmin.

Differential diagnosis
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  • Late stage intravascular (nodular) fasciitis
  • Vascular Leiomyomas
  • Plexiform fibrohistiocytic tumors
  • plastic penis induratio

Progression/forecast
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Even with incomplete removal, the tumour does not tend to recur.

Literature
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  1. Fetsch JF et al (2000) A distinctive myointimal proliferation ('myointimoma') involving the corpus spongiosum of the glans penis: a clinicopathologic and immunohistochemical analysis of 10 cases. Am J Surg Pathol 24:1524-1530.
  2. McKenney JK et al (2007) Penile myointimoma in children and adolescents: a clinicopathologic study of 5 cases supporting a distinct entity. At J Surg Pathol 31:1622-1626.
  3. Robbins JB et al (2005) Penile nodule in a 54-year-old man: a case of a myointimoma. J Am Acad Dermatol 53:1084-1086.
  4. Turner BM et al (2009) Penile myointimoma. J Cutan Pathol 36:817-819.
  5. Vardar E et al. (2007) Myointimoma of the glans penis. Pathol Int 57:158-161.

Outgoing links (1)

Plastic penis induratio;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020