Mohs chemo surgery

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Mohs introduced classical chemosurgery in 1941, which is rarely used in its original form today. See also microscopically controlled surgery.

Implementation
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  • Tissue fixation in situ with dichloroacetic acid or 50% trichloroacetic acid to increase permeability, followed by zinc chloride paste as fixative. After 24 hours, fixed tissue can be painlessly removed in horizontal incisions. Histological control and, if necessary, post-excision until there is no edge incision. Secondary healing was recommended by Moh in order not to cover recurrences of high-risk tumours by flap plasty.
  • Today, the procedure is generally used as a fresh tissue technique without the painful zinc chloride fixation.

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Last updated on: 29.10.2020