Mib1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Monoclonal antibody for immunohistochemical staining of the KI-67 protein, e.g. in tumor cells. Proliferation marker. MIB1 can be given as proliferation index: MIB1 positive cells/ 100 tumor cells. The lower the index, the lower the proliferation activity (growth activity) of the tumour tissue. For malignant melanoma, the localization of the Ki-67 protein (junctional area or in the area of the basal sections of the tumor) also plays a diagnostic role.

General information
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Can be detected on paraffin material.

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Last updated on: 29.10.2020