Melanocytosis dermal (overview) D22.-

Benign, congenital or in the first months of life manifesting, rarely later acquired (acquired dermal melanocytosis), blue to blue-grey spots or patches, which are characterized histologically by a proliferation of dermal, pigmented, spindle and/or dendritic cells.

The following subdivision can be made according to their distribution pattern:

• Mongolian spot
• Naevusfuscocoeruleus ophthalmomaxillaris (Naevus Ota)
• Nevus fuscocoeruleus deltoideoacromialis (nevus Ito)
• Acquired dermal melanocytosis (ADM) - (back, nose, hands)

Combination with other malformations (see below the respective clinical pictures).

There is a tendency to regress during childhood. Acquired dermal melanocytosis persists throughout life.

1. Baroody M, Holds JB (2004) Extensive locoregional malignant melanoma transformation in a patient with oculodermal melanocytosis. Plast Reconstr Surg 113: 317-322.
2. Goncharuk V et al. (2003) Bednar tumor associated with dermal melanocytosis: melanocytic colonization or neuroectodermal multidirectional differentiation? J Cutan Pathol 30: 147-151.
3. Grimaux X et al. (2020) An unusual brownish patch on the back of a 74-year-old Caucasian man. J Dtsch Dermatol Ges 18:638-640.
4. Hanson M et al. (2003) Association of dermal melanocytosis with lysosomal storage disease: clinical features and hypotheses regarding pathogenesis. Arch Dermatol 139: 916-920
5. Rubin AI et al. (2001) Acquired dermal melanocytosis: appearance during pregnancy. J Am Acad Dermatol 45: 609-613