Megluminantimonate

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Dosage and method of use
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Remember! Maximum dose 850 mg/day!

  • Visceral Leishmaniasis: 20 mg/kg bw/day for at least 20 days (until no more parasites can be detected).
  • Cutaneous leishmaniasis (except L. aethiopica, brasiliensis, guyanamensis):
    • Local therapy: Injection of 1-3 ml under the ulcer, possibly 1-2 scds at intervals of 1-2 days.
    • Systemic: 10-20 mg/kg bw/day until the smears are negative and then another 3 days.
  • Cutaneous leishmaniasis (L. brasiliensis): 20 mg/kg bw/day until the lesion is healed (max. 4 weeks).
  • Mucocutaneous leishmaniasis: 20 mg/kg bw/day until the smear is negative (max. 4 weeks).
  • Diffuse cutaneous leishmaniasis: 20 mg/kg bw/day until clinical improvement occurs (usually for months).

Preparations
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Glucantime (available through the international pharmacy).

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Last updated on: 29.10.2020