Kaposi's sarcoma epidemic C46.-

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

HIV-associated Kaposi sarcoma; Sarcoma idiopathicum multiplex

Definition
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Rare multifocal angioproliferative neoplasia occurring primarily in the skin and secondarily also in other organs. Kaposi's sarcoma occurs spontaneously or as part of an HIV infection (infectious angiogenesis).

Occurrence/Epidemiology
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Incidence of HIV-associated, epidemic Kaposi sarcoma: in 5-7% of HIV-infected persons. In earlier times of epidemic Kaposi's sarcoma that could not be treated adequately, the incidence was > 25% of HIV-infected persons.

Etiopathogenesis
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Localization
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Predilection sites are the face (tip of the nose), trunk, genitals, oral mucosa.

Clinical features
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Initially brown-red to violet spots, from which plaque-like and nodular tumours develop. Tendency to confluence and formation of new foci in the marginal area. Tendency to ulceration (especially mucous membrane lesions). In case of trunk infestation mostly exanthematic spread of the skin lesions with characteristic arrangement along the skin cleft lines. Disturbed lymph drainage leads to elephantiasis-like oedemas. Infestation of lymph nodes, more rarely of the gastrointestinal tract, liver, lungs or heart is possible.

Histology
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Literature
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Outgoing links (1)

Kaposi's sarcoma (overview);

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020