Inosine

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 17.11.2022

Dieser Artikel auf Deutsch

Synonym(s)

Dimepranol; Dimepranol acetamidobenzoate

Definition
This section has been translated automatically.

Synthetic derivative of purine with immunomodulatory and virustatic properties. Intermediate product of purine metabolism (purine nucleoside). Effectiveness is controversial.

Indication
This section has been translated automatically.

For immune stimulation in viral diseases, especially subacute sclerosing panencephalitis, herpes simplex, zoster, measles, cytomegaly and Epstein-Barr virus infection.

Pregnancy/nursing period
This section has been translated automatically.

Strict indication position! There is no sufficient experience with pregnant women or mothers in the lactation period.

Dosage and method of use
This section has been translated automatically.

  • Herpes simplex infections: adults 6-8 tbl/day depending on the severity of the disease (one tbl every 2-3 hours), children 1/2-6 tbl spread over several doses throughout the day (50-100 mg active substance/kg bw/day).
  • Viral infections in immunocompromised patients: adults: 50 mg divided into 3-5 doses, children 100 mg active substance mixture/kg bw/day divided into 2-4 doses.

Undesirable effects
This section has been translated automatically.

Temporary increase of the uric acid level in serum and urine (caused by the metabolism of inosine) Allergic reactions to inosine or other ingredients of the drug preparation (especially urticaria, erythema), in very rare cases anaphylactic shock.

Contraindication
This section has been translated automatically.

Purine metabolism disorders (gout, hyperuricemia), renal insufficiency, urinary and kidney stone disorders, tendency to extrasystoles, cerebral seizure disorders, gastric disorders, autoimmune disorders and celiac disease.

Preparations
This section has been translated automatically.

Isoprinosines

Authors

Last updated on: 17.11.2022