Immotile ciliae syndrome N46.x

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Disturbance of the locomotor system of the spermatozoa as well as the ciliated epithelium in the respiratory tract due to various genetic structural defects of the cilia.

Manifestation
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Family clustering, mode of inheritance still unknown.

Clinical features
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Sterility due to strongly restricted progressive movement of the spermatozoa. Recurrent bronchitis and pneumonia since childhood, bronchiectasis.

Diagnosis
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Ejaculate examination, electron microscopic examination of sperm, lung clearance (scintigraphic).

Therapy
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No causal therapy possible, symptomatic therapy of pulmonary symptoms.

Literature
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  1. Hönig-Gerhold I, Krause W, Aumüller G (1987) Immotileciliae syndrome. dermatologist 38;:738-739

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Cartagenic syndrome;

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Last updated on: 29.10.2020