Ichthyosis acquisita (pseudoichthyosis) - Altmeyers Encyclopedia

Synonym(s)

Acquired ichthyosis; acquired icthyosis; Ichthyosis acquired; Pseudoichthyosis; Pseudo-Ithyosis; Skin changes symptomatic ichthyosiform; symptomatic ichthyosis

Definition
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Non-hereditary ichthyosiform skin changes in the context of other diseases or due to incorrect, drying, usually exaggerated skin care. In rare cases also occurring as a paraneoplastic syndrome.

Etiopathogenesis
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See Table 1.

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Dermatology

Pyoderma

Acute or chronic infection of the epidermis (impetigo contagiosa) and possibly also of the various skin app...

Therapy
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Treatment of the underlying disease. General and external therapy according to ichthyosis vulgaris, autosomal dominant.

Tables
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Etiology	Associated clinical pictures/occurrence
Excessive false cleansing processes	V.a. in elderly people
Malignancies	Hodgkin and non-Hodgkin lymphomas, breast carcinomas, lung carcinomas, cervical carcinomas, leiomyosarcomas, Kaposi's sarcoma
Renal insufficiency	e.g. dialysis
Autoimmune diseases	Systemic lupus erythematosus, dermatomyositis, mixed collagenosis
Infectious diseases	HIV, tuberculosis
Medications	Lipid-lowering drugs, psychotropic drugs, cimetidine, clofazimine
Deficiencies	Vitamin A deficiency, cachexia
Hormone disorders	Hypothyroidism, hyperparathyroidism, panhypopituitarism
Chronic inflammatory diseases	M. Crohn's disease, proctocolitis

Literature
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DiGiovanna JJ et al (2003) Ichthyosis: etiology, diagnosis, and management. At J Clin Dermatol 4: 81-95
Eisman S et al (2003) Granulomatous mycosis fungoides presenting as an acquired ichthyosis. Clin Exp Dermatol 28: 174-176
Kütting B et al (1995) The acquired ichthyosis-like skin condition. dermatologist 46: 836-840
Rizos E et al (2002) Acquired icthyosis: a paraneoplastic skin manifestation of Hodgkin's disease. Lancet Oncol 3: 727