Hypromellose
Synonym(s)
Hydroxypropylmethylcellulose; Hypromellosum PhEur; Methylhydroxypropyl cellulose
Definition
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Hypromellose, also called methylhydroxypropyl cellulose, is a partially O-methylated and O-(2-hydroxypropylated) cellulose. It is available as white, yellowish-white or greyish-white powder or in granular form.
Hypromellose is virtually insoluble in hot water; in cold water it dissolves to form a colloidal solution.
Indication
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Sjögren's syndrome, keratoconjunctivitis sicca, wetting/rewetting of soft and hard contact lenses (also suitable for patients who cannot tolerate artificial tear substitutes or contact lens wetting agents!)
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Dosage and method of use
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Apply 1 trp. into the conjunctival sac 3-5 times/day or more often.
Standard concentration
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0.3-2% in eye drops.
Recipe(s)
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Hypromellose-adhesive paste 40% (NRF 7.8.)
Preparations
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Sicca-Stulln, Artelac eye drops, Berberil Dry Eye drops
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Prof. Dr. med. Peter Altmeyer