Hyperpigmentation periocular L81.4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 21.04.2021

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Circles under the eyes; Dark circles under the eyes; Familial periorbital hyperpigmentation; Halonated eyes; Periocular hyperpigmentations; Periorbital hyperpigmentation

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Periocular, primarily cosmetically disturbing pigment proliferation of different etiology. Hyperpigmentation increases with age. It occurs more frequently in families.

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    A distinction is made between the following forms:

    • Idiopathic hyperpigmentation without disease value, which is observed mainly in Afro-Americans, South and East Asians, North Africans.
    • Hyperpigmentation in atopic diathesis (minor criterion). Grey-brown discolouration in the periocular region (haloed eyes).
    • Genetically determined periocular pigment proliferation without concomitant disease (familial occurrence especially in persons with dark complexion).
    • Chloasma hepaticum (masque biliare)
    • hyperpigmentation as an indication of hyperthyroidism (see also Jellinek's sign)
    • Drug-induced pericocular hyperpigmentation with the use of prostaglandin-containing eye drops (these may also be contained in cosmetic eyelash extensions). Differentially, the shading in blepharochalasis has to be considered.

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    1. Treatment of the underlying disease. Brightening preparations with hydroquinone (3% hydroquinone ointment), azelaic acid, kojic acid or arbutin.


    Please ask your physician for a reliable diagnosis. This website is only meant as a reference.


    Last updated on: 21.04.2021