Hydralazine disease T88.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 23.12.2020

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Definition
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Symptoms of disease after prolonged treatment with hydrazinophthalazine (lowering blood pressure) in 8-10% of cases.

Clinical features
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Image of systemic lupus erythematosus with transient erythema, urticarial itchy eruptions, punctiform hyperkeratosis, especially in the face and hands. Swelling of lymph nodes, splenomegaly, pericarditis, pleuritis, atypical pneumonia, kidney involvement.

Laboratory
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Albuminuria, hematuria, cylinduria, leukopenia, gamma globulinemia, ANA positive. See also pseudo-SLE syndrome.

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Lung diseases, skin changes;

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Last updated on: 23.12.2020