Ganglioneuroma D36.18

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Gangliocytoma; Ganglioneuroblastoma; Neuroma gangliocellular

Definition
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Benign neuromas that occur extremely rarely on the skin and originate from sympathetic nerves.

Manifestation
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Mainly early childhood, partly in the context of neurofibromatosis.

Localization
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Paravertebrally on the back and in the neck area (starting from the borderline strand).

Clinical features
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Extremely rare, solitary or multiple, pea-sized to child's head, subcutaneously located, prallelastic, asymptomatic (not painful) nodules, which can be clinically mistaken for lipomas.

Histology
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Ganglion cells embedded in a myxoid stroma, partly lymphocyte-like, partly larger ganglion cells, joined together to form synzytial eosinophilic clusters, usually accompanied by numerous mast cells. The histological picture can easily be confused with a myxofibroma.

Therapy
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Neurosurgical, with cutaneous manifestation possibly simple excision.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020