Friction amyloidosis

Last updated on: 07.11.2026

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Definition
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Cutaneous amyloidosiscaused by constant scratching and rubbing of certain, usually chronically itchy areas of skin with hard brushes or other objects (nylon brush macular amyloidosis/formation of amyloid K). There are pathogenetic links, among other conditions, tonotalgia paresthetica.  

Literature
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  1. Soriano LF et al. (2018) An intensely pruritic pebbled presentation. Dermatol Online J 24:13030/qt6tp6f9c4.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Last updated on: 07.11.2026