Fansimef
Definition
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Antimalaria drug not approved in Germany, combination preparation of mefloquine (250 mg), sulfadoxine (500 mg) and pyrimethamine (25 mg) per tbl.
Half-life
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4–16 h
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Indication
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Chloroquine-resistant malaria through Pl. falciparum.
Dosage and method of use
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- Non-immune adults and adults with > 60 kg bw: 3 tbl/day.
- Adults < 60 kg KG and children 10-14 years (31-45 kg): 2 tbl/day
- children 7-9 years (21-30 kg): 1 1/2 dbl/day
- children 4-6 years (11-20 kg): 1 dbl./day
- children < 4 years (5-10 kg): 1/2 dbl/day
Undesirable effects
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Interactions
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Contraindication
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Hypersensitivity to one of the ingredients, blood formation disorders, epilepsy, newborns.
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Prof. Dr. med. Peter Altmeyer