Erythromycine cream hydrophilic 0.5/1/2 or 4% (nrf 11.77.)

Keywords

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Formulation

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Hydrophilic 1-4% erythromycin cream (O/W cream), for external use if no drying effect of the base is desired. Apply a thin layer 1-2 times/day to previously cleansed skin.

Shelf life: tube/dispenser: 2 months when stored in the refrigerator

Entries in which this recipe is mentioned:

• Eczema, seborrheic
• Erythrasma
• Erythromycin
• Erythromycin cream 1/2 or 4% (NRF 11.77.)
• Pyoderma faciale
• zoster
• Acne papulopustulosa

Note: Erythromycin cream is used as a combination therapy together with tretinoin or isotretinoin for acne papulopustulosa. Especially for this skin disease, the base cream DAC proves to be too greasy, which is why it is diluted with propylene glycol and water in NRF regulation 11.77. This mixture corresponds to the diluted cream DAC. This mixture corresponds to the Diluted Base Cream DAC, which can also be purchased ready-made. Since the update 2025/2, this standardized base is additionally considered in the NRF regulation.

Erythromycon tends to clump, especially at higher concentrations of active ingredient. Erythromycin is carefully rubbed with medium-chain triglycerides during preparation in the Fanta dish. If the pharmacy works with semi-automatic and fully automatic stirring systems, erythromycin is first thoroughly rubbed in with a little base. For stability reasons, Hydrophilic Erythromycin Cream is stored in the refrigerator!