Erythema palmoplantare hereditarium Q27.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Erythema palmare et planttare hereditarium; Erythema palmo-plantar; Familial palmoplantar erythema; Lane's disease; Lane syndrome; maladie de v. Bechterew-Stoelzner; Palmar Syndrome; Red Palmae Syndrome; red palms

History
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Lane, 1929

Definition
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Symmetrical, chronic, extensive reddening of the palms of the hands and soles of the feet.

Etiopathogenesis
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Autosomal dominant inherited disorder of palmo-plantar blood flow caused by dysplasia of the skin vessels. Pathogenetically, the clinical appearance is caused by a strong proliferation and anastomosis of the capillaries.

Manifestation
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Predominantly occurring in the male sex. First symptoms already in early childhood.

Localization
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Mainly palms, mainly thenar, hypothenar and fingertips, also soles of feet.

Clinical features
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Chronic, localized, symptomless, flat, 4.0 to 10.0 cm large, intensely red spots (erythema), which occur mainly on thenar and hypothenar, but also on fingers. Recess of the palm. The back of the hand is always recessed. Spots on the soles of the feet can only be detected discreetly.

Differential diagnosis
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Therapy
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Not known and also not useful.

Literature
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  1. Durieux-Verde M et al (2016) Erythema palmare hereditarium (Lane's disease): Report of a paediatric case. Ann Dermatol Venereol 143:32-5.
  2. Lane JH (1929) Erythema palmare hereditarium (red palms). Arch Derm Syph (Chicago) 20: 445-448

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Last updated on: 29.10.2020