HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Very rare, benign growth of endometric glandular tissue and stroma in the skin.
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Occurrence/EpidemiologyThis section has been translated automatically.
Very rare occurrence.
The estimated incidence of umbilical endometriosis is 0.5-1.0% of all extragenital endometrial ectopias (Note: about 10-15% of women of reproductive age suffer from endometriosis). In a larger study (n=33 women) the mean age of onset of cutaneous endometriosis was 35.4 ± 2.33 years (Lopez-Soto A et al. 2018).
EtiopathogenesisThis section has been translated automatically.
About 70% of all cutaneous endometrioses develop secondarily in surgical scars. The most widespread assumption is therefore that the disease is preceded by the iatrogenic implantation of endometric cells through surgical procedures. In the case of spontaneous cutaneous endometriosis, the carry-over of endometrial particles via the blood or lymph channels is postulated.
ManifestationThis section has been translated automatically.
Sexually mature women, especially after the age of 35. The average age in larger studies was 34.6 years.
LocalizationThis section has been translated automatically.
Mainly umbilical, inguinal and genital regions, often in surgical scars of the caesarean section.
Clinical featuresThis section has been translated automatically.
Mostly over several years slowly growing, surface-smooth, 0.5-3.0 cm large, soft to bulging elastic nodes of lighter to darker blue or red colouring; often cyclical premenstrual feeling of tension or also (distinct) pain (in about 50% of patients). Recurrent inflammation and bleeding may also occur.
HistologyThis section has been translated automatically.
The bioptate shows glandular and stroma tissue of the uterine mucosa
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Claas-Quax MJ et al (2015) Primary umbilical endometriosis. Eur J Obstet Gynecol Reprod Biol 194:260-261
- Costa IM et al (2014) Cutaneous endometriosis: dermoscopic findings related to phases of the female hormonal cycle. Int J Dermatol 53:e130-132
- DeClerck BK et al (2012) Cutaneous decidualized endometriosis in a nonpregnant female: a potential pseudomalignancy. At J Dermatopathol 34:541-543
- Fernández Vozmediano JM et al (2010) Cutaneous endometriosis. Int J Dermatol 49: 1410-1412
- Lopez-Soto A et al (2018) Cutaneous endometriosis: Presentation of 33 cases and literature review.
- Eur J Obstet Gynecol Reprod Biol 221:58-63.
- Mohr M et al (2015) Cycle dependent painful tumor in the navel. Dermatologist 66: 961-963
- Nguessan KL et al (2014) Spontaneous cutaneous umbilical endometriosis: a rare variant of extragenital endometriosis. Clin Exp Observed Gynecol 41:486-488
- Russo VA et al (2015) Painful nodule in the caesarean section scar of a youngwoman. Dermatol Online J 21 pii:13030/qt4rn7q88d
- Uçar MG et al.(2015) Surgical Treatment of Scar Endometriosis Following Cesarean Section, a Series of 12 Cases. Indian J Surg 77(Suppl 2): 682-686
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