Dexketoprofen

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Analgesic and anti-rheumatic. Non-steroidal anti-inflammatory. Derivative (racemate) of ketoprofen.

Indication
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Short-term therapy of light to moderately strong pain, such as pain of the locomotor system, menstrual pain, toothache.

Pregnancy/nursing period
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Contraindicated during pregnancy (risk of contractions and premature closure of the ductus arteriosus botalli) and lactation (substance passes into breast milk).

Dosage and method of use
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12.5 mg p.o. every 4-6 hours, depending on the intensity of pain. Alternatively 3 times/day 25 mg p.o. Maximum daily dose: 75 mg. Best taken 30 minutes before meals with sufficient liquid.

Undesirable effects
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  • Occasionally (1-10% of patients): Gastrointestinal symptoms such as heartburn, loss of appetite, nausea, vomiting, abdominal pain.
  • Rarely (1-10% of patients): Cutaneous side effects such as maculopapular exanthema, urticaria, acneiform complaints, photosensitivity. Rarely (about 1% of patients): fatigue, hot flushes.

Contraindication
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Children/adolescents < 18 years (no therapy experience, insufficient data). Hypersensitivity or photoallergic reactions to the substance or cross-reactions to fibrates or other NSAIDs. Active stomach or intestinal ulcers, gastrointestinal bleeding. Severe liver or kidney failure.

Preparations
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Sympal

Note(s)
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Remember! The ability to react in road traffic and when operating machines may be impaired!

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Last updated on: 29.10.2020