Dermatophytosis syndromeB35.3

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Trichophyton rubrum syndrome; Trichophyton-rubrum syndrome

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HistoryThis section has been translated automatically.

Zaias, 1996

DefinitionThis section has been translated automatically.

Recurrent, usually lifelong, chronic tinea of the soles of the feet and/or distal subungual tinea unguium and/or tinea corporis.

PathogenThis section has been translated automatically.

Especially Trichophyton rubrum.

ClassificationThis section has been translated automatically.

Criteria for the Trichophyton rubrum syndrome (according to Korting):
  • Skin infestation with Trichophyton rubrum on hand, foot, nail and one other localization (except inguinal).
  • In each case positive native preparation
  • In each case positive culture from the material of at least three localisations.

Clinical featuresThis section has been translated automatically.

Usually less symptomatic, chronically persistent, extensive, scaly and itchy erythema on the feet, inguinal region and other body regions. Onychomyotic infestation of the foot and fingernails.

DiagnosisThis section has been translated automatically.

Mycological culture; clarification of an immunodeficiency.

General therapyThis section has been translated automatically.

Prevention and treatment of sources of infection such as infected animals e.g. cats, dogs, cows, guinea pigs.

External therapyThis section has been translated automatically.

S.u. Tinea, see below Antimycotics.

Internal therapyThis section has been translated automatically.

  • Indication for systemic therapy with broad-spectrum antifungal agents with very high corneal patency is always given. Duration of therapy 2-3 months or longer, until complete remission of symptoms. Trial with itraconazole (e.g. Sempera Kps.) 1mal/day 100 mg p.o.
  • Alternative: Fluconazole (e.g. Diflucan Kps.) 1-2 times/day 200-400 mg p.o.
  • Alternative: Terbinafine (e.g. Lamisil Tbl.) 1 time / day 250 mg p.o.
  • Alternative: Griseofulvin (e.g. Likuden Tbl.) 1 time / day 500 mg p.o., in severe cases 750-1000 mg/day p.o.

ProphylaxisThis section has been translated automatically.

S.u. Tinea.

LiteratureThis section has been translated automatically.

  1. Böhmer U et al (1999) Trichophyton-rubrum syndrome with tinea axillaris as partial manifestation. Dermatologist 50: 292-294
  2. Brasch J et al (1990) Pathogen and pathogenesis of dermatophytosis. Dermatologist 41: 9-15
  3. Drake LA et al (1996) Guidelines of care for superficial mycotic infection of the skin: Tinea corporis, tinea cruris, tinea faciei, tinea manuum tinea pedis. J Am Acad Dermatol 34: 282-286
  4. Kick G et al (2001) The definition of Trichophyton rubrum syndrome. Mycoses 44: 167-171
  5. Zaias N et al (1996) Chronic dermatophytosis caused by Trichophyton rubrum. J Am Acad Dermatol 35: 614-617

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Last updated on: 29.10.2020