Cytokeratin 18

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

CK18; CK8

Definition
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Cytokeratin 18 (analogous behaviour also applies to cytokeratin 8) is a reliable marker for simple secretory (glandular and ductal) epithelia, reliable marker of Paget' s disease and numerous sweat gland tumours as well as basal cell carcinoma. Not marked are keratinizing epithelia and spinocellular carcinomas.

Literature
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  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 33.

Outgoing links (1)

Paget's disease of the nipple;

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Last updated on: 29.10.2020