DefinitionThis section has been translated automatically.
Very rare, carcinomatous degeneration of a usually preexisting cylindroma. Metase formation is possible (Pichler M et al. 2021).
ManifestationThis section has been translated automatically.
Often occurring in association with Brooke-Spiegler syndrome (Pichler M et al. 2021) .
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LocalizationThis section has been translated automatically.
Mainly capillitium, neck, neck, face, rarely trunk and extremities.
Clinical featuresThis section has been translated automatically.
Mostly at the base of a cylindromatosis (Brooke-Spiegler syndrome), rarely occurring in solitary tumours. Some of the pre-existing cylindromes, which are unusually large (3-5 cm), bulging, protuberant, flesh-coloured nodes, show rapid spontaneous growth with ulceration. Tendency to grow into deep, localized structures (e.g. under bones).
HistologyThis section has been translated automatically.
The distinct picture of the benign cylindrome is mostly still detectable. Blurred, asymmetrical, roundish or elongated basaloid cell complexes are visible, which fill the entire dermis as well as the adjacent parts of the subcutis. The cell nests consist of polymorphic basaloid elements with numerous mitoses. Typical are circumscribed mass necroses (see also Porom).
TherapyThis section has been translated automatically.
Excision with a safety margin (see spinocellular carcinoma below).
LiteratureThis section has been translated automatically.
- Delgado R et al (2003) Sentinel lymph node analysis in patients with sweat gland carcinoma. Cancer 97: 2279-2284
- Durani BK et al (2001) Malignant transformation of multiple dermal cylindromas. Br J Dermatol 145: 653-656
- Pichler M et al (2021) Metastatic cylindrocarcinoma in Brooke-Spiegler syndrome - Report of a case and review of the literature. J Dtsch Dermatol Ges 19:125-128.
- Rutten A (2002) Eccrine sweat gland carcinoma of the skin. Pathologist 23: 79-88
- Schmaltz R et al (2010) Sudden size growth of previously indolent nodules on the capillitium. Dermatologist 61: 518-622
- Volter C et al (2002) Cylindrocarcinoma in a patient with Brooke-Spiegler syndrome. Laryngorhinootology 81: 243-246
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Outgoing links (4)
Brooke-spiegler syndrome; Cylindrome; Porom eccrines; Squamous cell carcinoma of the skin;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer