Cutaneous mastocytosis of adulthood

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 31.07.2023

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Definition
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Clinical features
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Flat, oval or round, grayish-brown or reddish-brown spots, 0.1-0.5 cm in size. After firm brushing of the lesions, there is an urticarial reaction in the foci(Darier's sign); more rarely, subepidermal blistering. Frequently, an elevated dermographism can also be triggered. Initially weak, later stronger lesional pigmentation. The most frequent accompanying symptom is itching.

Special forms of cutaneous mastocytosis of adulthood:

Complication(s)
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Mastocytosis patients show a high prevalence of anaphylaxis and are often diagnosed for the first time via these (Gülen T et al. 2017). Main triggers for anaphylaxis in adults are insect bites (19%), food (16%) and drugs (9%).

Literature
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  1. Gülen T et al (2017) Risk Factor Analysis of Anaphylactic Reactions in Patients With Systemic Mastocytosis. J Allergy Clin Immunol Pract 5:1248-1255.

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Last updated on: 31.07.2023