Curly hair acquired L67.

Acquired (see also frizzy hair syndrome, with frizzy hair - woolly hair, curly hair- as a symptom in complex malformation syndromes) hair condition with frizzed hair shafts. Hair usually lacks shine, is rough and cannot be styled. The curly hair can be based on different hair shaft anomalies like: Pili torti, Pili canaliculi. Curly hair can also appear as an isolated, circumscribed malformation of the scalp (see curly hair nevus below).

Acquired frizzy hair (hair curling) can occur in connection with the use of various medications. These include:
Alitretinoin, etretinate, isotretinoin, valproic acid, indinavir, EGFR tyrosinase inhibitors (gefitinib, erlotinib). Idiopathic hair curling has also been described in healthy adolescents. Hair curling is also a phenomenon that is observed in regrowing hair after cytostatic therapy.

1. Camacho-Bragado GA et al (2015) Understanding breakage in curly hair. Br J Dermatol 173 Suppl 2:10-16
2. Herink C et al (2015) Development of curly hair under systemic therapy with alitretinoin. dermatologist 66: 617-619
3. Morice-Picard F et al (2013) Cutaneous manifestations in Costello and cardiofaciocutaneous syndrome: report of 18 cases and literature review. Pediatric Dermatol 30:665-67
4. Zheng S et al (2009) Gefitinib-induced hair alterations. BMJ Case Rep. doi: 10.1136/bcr.09.2008.0878.