Congenital deficiency of leukocyte-adherence glycoprotein D84.9
Synonym(s)
CDLG
Definition
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Congenital immune defect with disturbed leukocyte function and tendency to infection.
Clinic
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Pyoderma gangraenosum, skin necrosis, ulcerations, impaired wound healing, gingivitis, stomatitis, otitis media, pneumonia, etc.
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Therapy
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No causal therapy known. Symptomatic treatment of the skin changes and infections.
Progression/forecast
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30% lethality.
Literature
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- Bedlow AJ et al (1998) Pyoderma gangrenosum in a child with congenital partial deficiency of leucocyte adherence glycoproteins. Br J Dermatol 139: 1064-1067
- Kerkhof PCM, Weemaes CMR (1990) Skin manifestation in congenital deficiency of leukocyte-adherence glycoprotein (CDLG). Br J Dermatol 123: 395-401
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Cdlg;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer