Clear cell hidradenoma D23.L

Benign adnexal tumor with apocrine (and eccrine?) differentiation. S.u. Hidradenoma.

Clear (or light) cell variant of the nodular hidradenome

Occurring in adulthood.

Face, head hair, skin, chest area.

Predominantly solitary tumour, up to 3 cm in size, fused with the epidermis, easily displaceable towards the subcutis, partly solid, partly cystic. Central ulceration is possible.

Lobularly arranged epithelioid cells in the corium. Cavities, plant cell-like, hydrophobic-clear cells with sharply defined cytoplasmic membrane.

Fibroma, nevus, clear cell lacanthoma,

Excision with small safety distance (5 mm) is curative.

Rarely is the occurrence of malignant degeneration with locally destructive growth possible.

1. Ambrojo P et al (1989) Clear-cell syringoma. Dermatologica 178: 164-166
2. Faulhaber D et al (2000) Clear cell hidradenoma in a young girl. J Am Acad Dermatol 42: 693-695
3. Harada T (2003) Malignant clear-cell hidradenoma associated with pseudoepitheliomatous hyperplasia on the forehead. Ann Plast Surgery 50: 443-444
4. Sagi A et al (2002) Cystic clear cell hidradenoma of the thumb: case report of a rare hand tumor. Ann Plast Surgery 48: 337-338
5. Will R et al (2000) Recurrent clear cell hidradenoma of the foot. Dermatol Surgery 26: 685-686