Clear cell hidradenoma D23.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Bright cell myoepithelioma; clear cell hidradenoma; Clear cell myoepithelioma

Definition
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Benign adnexal tumor with apocrine (and eccrine?) differentiation. S.u. Hidradenoma.

Etiopathogenesis
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Clear (or light) cell variant of the nodular hidradenome

Manifestation
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Occurring in adulthood.

Localization
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Face, head hair, skin, chest area.

Clinical features
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Predominantly solitary tumour, up to 3 cm in size, fused with the epidermis, easily displaceable towards the subcutis, partly solid, partly cystic. Central ulceration is possible.

Histology
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Lobularly arranged epithelioid cells in the corium. Cavities, plant cell-like, hydrophobic-clear cells with sharply defined cytoplasmic membrane.

Differential diagnosis
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Therapy
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Excision with small safety distance (5 mm) is curative.

Progression/forecast
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Rarely is the occurrence of malignant degeneration with locally destructive growth possible.

Literature
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  1. Ambrojo P et al (1989) Clear-cell syringoma. Dermatologica 178: 164-166
  2. Faulhaber D et al (2000) Clear cell hidradenoma in a young girl. J Am Acad Dermatol 42: 693-695
  3. Harada T (2003) Malignant clear-cell hidradenoma associated with pseudoepitheliomatous hyperplasia on the forehead. Ann Plast Surgery 50: 443-444
  4. Sagi A et al (2002) Cystic clear cell hidradenoma of the thumb: case report of a rare hand tumor. Ann Plast Surgery 48: 337-338
  5. Will R et al (2000) Recurrent clear cell hidradenoma of the foot. Dermatol Surgery 26: 685-686

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020