DefinitionThis section has been translated automatically.
Substance from the group of virustatics.
Half-lifeThis section has been translated automatically.
17 or 65 h (metabolites).
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IndicationThis section has been translated automatically.
Infections caused by cytomegaloviruses (including the untreated CMV retinitis), effective also against HSV and VZV.
Dosage and method of useThis section has been translated automatically.
Initial 5 mg/kg bw i.v. once/week for 2 weeks. Maintenance dose from week 3: 5 mg/kg bw i.v. once/14 days.
Remember!
Slow infusion for at least 1 hour. Due to the pronounced nephrotoxicity, administration of Probenicid 2 g three hours before and 1 g two and eight hours after Cidovofir. Immediately before the administration of cidofovir, 1 litre of 0.9% NaCl solution must be infused!Undesirable effectsThis section has been translated automatically.
At systemic application: nausea, fever, alopecia, muscle pain.
Cave! Probenicide intolerance (exanthema, pruritus, nausea, vomiting, headache)
PreparationsThis section has been translated automatically.
Vistide
Prof. Dr. med. Peter Altmeyer