Chromosome deletion

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 27.07.2021

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Synonym(s)

Deletion

Definition
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Deletion is the loss of a nucleic base or a segment from the DNA strand. Interstitial deletion means loss of fragments within a chromosome in contrast to terminal deletion, where end segments of a chromosome are lost.

As a result, a defective protein can arise from the mRNA after translation. If an entire codon/base triplet is removed, a defective protein will most likely result because an amino acid is missing. If the deletion affects only a single base pair, it is also called a point mutation.

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Point mutation;

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Last updated on: 27.07.2021