Chlorhexidine digluconate

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

INCI designation: Chlorhexidine Digluconate.

Definition
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It is used as a disinfectant and preservative in cosmetics and pharmaceuticals (see also stomatological products). Also used for disinfection of hands and wounds.

Undesirable effects
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Contact allergic eczema is described; furthermore anaphylactic reactions after local application in the mucosal area (catheterisation). Chlorhexidine digluconate is represented as a substance in the epicutaneous test series"disinfectant".

Literature
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  1. Kallen AJ et al (2011) Intolerance of chlorhexidine as a skin antiseptic in patients undergoing hemodialysis. Infect Control Hosp Epidemiol 32:1144-1146
  2. Liippo J et al (2011) The relevance of chlorhexidine contact allergy. Contact Dermatitis 64: 229-234
  3. Noel J et al.M (2012) A case report of anaphylaxis to chlorhexidine during urinary catheterisation. Ann R Coll Surg Engl 94:e159-160
  4. Toholka R et al (2013) Allergic contact dermatitis to chlorhexidine. Australas J Dermatol 54:303-306

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Last updated on: 29.10.2020