Centellae asiaticae herba

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 18.12.2020

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Synonym(s)

Water pennywort Asian

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DefinitionThis section has been translated automatically.

Centellae asiatica herbae, the water navel herb, is the officinal preparation (Ph.Eur.8) of the Asian water navel, consisting of the crushed and dried aerial parts of the plant.

IngredientsThis section has been translated automatically.

Essential oils, flavonols, triterpene saponins and free triterpene acids (Asian acid, madacassic acid).

EffectsThis section has been translated automatically.

Antimicrobial, antiphlogistic, promotes wound healing; possibly inhibits excessive collagen proliferation (e.g. in scar keloids).

Field of application/useThis section has been translated automatically.

External: ointments and tinctures for wound and scar treatment;
Internal: tinctures as vein remedies

Trade namesThis section has been translated automatically.

In Germany approved preparations are not available. Available abroad as Madecasol® ointment and cream (1% active ingredient).

LiteratureThis section has been translated automatically.

  1. Leng DD et al (2013) In vivo disposition and metabolism of madecassoside, a major bioactive constituent in Centella asiatica (L.) Urb. J Ethnopharmacol 150:601-608.
  2. Lu GX et al (2014) Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice by downregulating collagen deposition. Phytother Res 28:1224-1231.
  3. Song J et al (2012) Madecassoside suppresses migration of fibroblasts from keloids: involvement of p38 kinase and PI3K signaling pathways. Burns 38:677-684.
  4. Wu F et al (2012) Identification of Major Active Ingredients Responsible for Burn Wound Healing of Centella asiatica Herbs. Evid Based Complement Alternat Med 2012:848093.

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Last updated on: 18.12.2020