Cd79a

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 10.06.2021

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Synonym(s)

B29; B-cell antigen receptor complex-associated protein alpha chain; CD79b; Iga; Ig-alpha; Igb; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein

Definition
This section has been translated automatically.

Pan B-lymphocyte marker (often more sensitive than CD20); B-cell lymphomas and leukemias.

CD79a, is a B cell receptor surface protein involved in the humoral immune response. CD79a is a cell type marker of B cells as well as their progenitor cells and is produced by B cells. It binds to CD79b. CD79a is necessary for cell differentiation of pro-B cells and pre-B cells.

CD79a is often used in combination with CD20 as a B cell marker for B cell lymphomas. Certain gene defects of CD79a are associated with a form of agammaglobulinemia.

Literature
This section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 28.

Outgoing links (1)

B-cell receptor;

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Last updated on: 10.06.2021