Bronopol

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

2-Bromo-2-nitro-propane-1,3-diol (INCI-Kennzeichnung)

Definition
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Preservative. Bronopol (BP) has an antiseptic and antimicrobial effect by splitting off formaldehyde. Bronopol is suitable for the application on the skin. It is used in household cleaners in dermatological preparations and cosmetics.

It is also found in various technical products (technical cutting emulsions, lubricants, detergents). Sensitizations are known (allergic contact eczema) but rare.

Literature
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  1. Choudry K et al (2002) Allergic contact dermatitis from 2-bromo-2-nitropropane-1,3-diol in Metrogel. Contact Dermatitis
  2. Choudry K, Beck MH, Muston HL. Allergic contact dermatitis from 2-bromo-2-nitropropane-1,3-diol in Metrogel. Contact Dermatitis 46:60-61
  3. Latorre N et al(2011) Patch testing with formaldehyde and formaldehyde-releasers: multicentre study in Spain (2005-2009). Contact dermatitis 65:286-292
  4. Schnuch A et al (2011) Contact allergy to preservatives. Analysis of IVDK data 1996-2009 Br J Dermatol 164:1316-1325

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Last updated on: 29.10.2020