Basophil granulation test
Synonym(s)
Basophil activation test; Rat fattening cell degranulation test
Definition
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In vitro detection system for histamine release from basophilic granulocytes. The allergen-specific stimulation is used to detect specific sensitization. The non-specific stimulation through the cell membrane of activating substances serves to verify the releaseability, i.e. the ability to release histamine.