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EtiopathogenesisThis section has been translated automatically.
Presumably disturbed regeneration of the auriculotemporal nerve after inflammatory or surgical lesion, mostly after parotid surgery. The disease occurs in 50-80% of patients following parotid operations, as well as after abscesses and facial injuries.
Misdirected regeneration of postganglionic parasympathetic nerve fibres, which run in the auriculotemporal nerve and the auricular nerve, in axons of damaged postganglionic sympathetic nerve fibres, which supply the sweat glands and the small skin vessels.
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Botulinum Toxin: A significant advance is the treatment with botulinum toxin. The subdivision of the hyperhidrotic areas ( Minorsch sweating test) into 2 × 2 cm boxes has proven to be effective. About 10 MU Dysport or 3 MU Botox (dilution: 500 MU Dysport or 100 MU Botox/5 ml 0.9% NaCl) are injected intradermally in a fan-shaped manner per box. The success of the therapy is monitored after 2-3 weeks. Remaining hyperhidrotic areas can be re-injected if necessary. Side effect: Painfulness of the injections.
Notice! Therapy with botulinum toxin belongs in the hands of an experienced doctor!
LiteratureThis section has been translated automatically.
- Burks W (2003) Skin manifestations of food allergy. Pediatrics 111: 1617-1624
- Eckardt A et al (2003) Treatment of gustatory sweating (Frey's syndrome) with botulinum toxin A. Head Neck 25: 624-628
- Frey L (1923) Le syndrome du nerf auriculo-temporal. Rev Neurol Paris 2: 97
- Hays LL, Novack AJ, Worsham JC (1982) The Frey syndrome: a simple, effective treatment. Otolaryngol Head Neck Surg 90: 419-425
- Laskawi R et al (2002) Frey's syndrome. Treatment with botulinum toxin. Curr Probl Dermatol 30: 170-177
- Milan JC (1967) Hereditary gustatory sweating. JAMA 201: 203-204
Incoming links (9)Aluminium chloride hexahydrate gel 15/20% (nrf 11.24.); Aluminium chloride hexahydrate solution, 15/20% 2-propanol (nrf 11.1.); Freysche's syndrome; Frey syndrome; Hyperhidrosis, gustatory; Hyperhidrosis, gustatory; Irritable syndrome; Sweat gland diseases (overview); Syndrome of the auriculotemporal nerve;
Outgoing links (5)Aluminium chloride hexahydrate gel 15/20% (nrf 11.24.); Aluminium chloride hexahydrate solution, 15/20% 2-propanol (nrf 11.1.); Botulinum toxin a; Hyperhidrosis (overview); Minor sweat test;
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