DefinitionThis section has been translated automatically.
EtiopathogenesisThis section has been translated automatically.
A variety of causes have been described, e.g. triggering by drugs such as tricyclic antidepressants (inhibition of flavokinase) or underlying diseases, which are frequently triggered by vitamin B2 deficiency.
Pathogenetically decisive is often the reduced vitamin B2 intake due to insufficient and unbalanced nutrition as well as due to absorption disorders in diseases of the gastrointestinal tract ( celiac disease, chronic enteritis) and changes in the physiological intestinal flora (e.g. antibiotic therapy).
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LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
- Integument: Eczematous, wet-crusted skin changes, rhagades. The lips are smooth, bright red and chapped, with weeping fissures covered with bark, cheilosis, perlèche, stomatitis, glossitis. The chronic eczematous changes of the genital region are called pellagroid scrotal dermatitis or vulvitis pellagrosa.
- Eye: Photophobia, fatigue, reduced visual acuity, vascularization of the cornea and pericorneal area, spots and opacities on the cornea.
- In the infant: growth and weight stagnation, desiccation.
DiagnosisThis section has been translated automatically.
External therapyThis section has been translated automatically.
Internal therapyThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Yates CA et al (2003) Absence of luminal riboflavin disturbs early postnatal development of the gastrointestinal tract. Dig Dis Sci 48: 1159-1164
Incoming links (9)Cheilosis; Oroculo-genital syndrome; Pellagra sine pellagra; Riboflavin; Riboflavin deficiency; Scrotal dermatitis, pellagroid; Vitamin b2 deficiency; Vitamins skin changes; Vulvitis pellagrosa;
Outgoing links (9)Celiac disease; Cheilosis; Eczema (overview); Erythema; Fissure; Glossitis; Perlèche (overview); Rhagade; Stomatitis;
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.