Apocrine hidrocystoma L75.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 22.03.2023

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apocrine cystadenoma; Apocrine cystadenoma; apocrine sweat gland cyst; Cystadenoma; Cyst of the lid margin; Eyelid cyst; Moll`s gland cyst; sudoriferous cyst; Sweat gland cyst

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Mehregan, 1964

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Benign cytic tumor occurring mainly periorbital. Apocrine hidrocystomas, in contrast to eccrine hidrocystomas, are often chambered and show apocrine secretion at least in sections. Differentiation is not always possible with certainty.

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Dermal, usually collapsed, secretion-filled epithelial cyst with two-rowed cubic epithelium. Basally, there are myoepithelial cells; luminally, there are linear arrangements of cylindrical cells with eosinophilic secretion deposits, a phenomenon typical for apocrine secretion (decapitation phenomenon).

Differential diagnosis
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Especially in the case of pigmented cyst contents, as a result of hemorrhage, the tumors can be confused with angiomas or blue nevi. Furthermore, differentiation from a cytic form of basal cell carcinoma is occasionally difficult.

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Excision for cosmetically or functionally disturbing cysts. Good results are also described withCO2 laser therapy. For multiple forms the use of pilocarpine or atropine is described (relatively unsatisfactory results).

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  1. Betti R et al (1994) Bilateral apocrine hidrocystoma of the eyelids. Dermatologist 45: 566-568
  2. del Pozo J et al (2001) Multiple apocrine hidrocystomas: treatment with carbon dioxide laser vaporization. J Dermatologist Treat 12: 97-100
  3. Hölig O et al. (1992) Multiple apocrine hidrokystomas. Nude Dermatol 18: 157-160
  4. Mehregan AH (1964) Apocrine cystadenoma; a clinicopathologic study with special reference to the pigmented variety Arch Dermatol 90: 274-279

Incoming links (2)

Cyst; Cystadenoma, apocrine;

Outgoing links (2)

Excision; Laser;


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Last updated on: 22.03.2023