Amphotericin b, liposomal

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Liposomal amphotericin

Definition
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Liposomal encapsulated Amphotericin B.

Indication
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Aspergillosis, cryptococcal meningitis ( cryptococcosis), if conventional amphotericin B therapy is contraindicated due to kidney damage or for other reasons

Limited indication
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Pregnancy, nursing.

Dosage and method of use
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On the 1st day 1 mg/kg bw i.v., then increase to 2-3 mg/kg bw, corresponding dosage in children.

Undesirable effects
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Compared to Amphotericin B rarely urea and creatinine increase. S.a.a. under Amphotericin B.

Contraindication
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Hypersensitivity to active substance or ingredients.

Preparations
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AmBisome

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Last updated on: 29.10.2020