Amphotericin b, liposomal
Synonym(s)
Liposomal amphotericin
Definition
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Liposomal encapsulated Amphotericin B.
Indication
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Aspergillosis, cryptococcal meningitis ( cryptococcosis), if conventional amphotericin B therapy is contraindicated due to kidney damage or for other reasons
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Limited indication
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Pregnancy, nursing.
Dosage and method of use
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On the 1st day 1 mg/kg bw i.v., then increase to 2-3 mg/kg bw, corresponding dosage in children.
Undesirable effects
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Compared to Amphotericin B rarely urea and creatinine increase. S.a.a. under Amphotericin B.
Contraindication
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Hypersensitivity to active substance or ingredients.
Preparations
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AmBisome